Testolone (RAD140)

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RAD-140, also called testolone, is a selective androgen receptor modulator (SARMS) that is in development by Radius Health, Inc. The medical goal of RAD-140 is to replace testosterone as part of hormone replacement therapy (HRT) without causing the usual side effects seen with exogenous testosterone, specifically those of androgenic nature. Therefore, it is not surprising that athletes have parlayed these benefits into helping them reach their fitness goals, contributing to testolone's growth in popularity.

How it works
If we simplify the idea behind this compound, RAD-140 was designed to behave like testosterone in the body, but without causing side effects. It does this by having a massive 85:1 anabolic to androgenic ratio. What's more, it also blocks the effects of testosterone in the prostate, limiting suppression and testes shrinkage.

Meanwhile, anabolic steroids that are derived from testosterone will have a tremendous impact on the reproductive system, including shutdown of the pituitary glands, or sending LH (luteinizing hormone) and FSH (follicle-stimulating hormone) levels to near 0 very quickly. As a result, many of those who abuse anabolic steroids will never be able to recover their natural hormonal levels, and will be forced to use hormone replacement therapy for the rest of their lives.

Athletic uses
A boost in testosterone within the body without the common steroid side effects leads to an increase in lean body mass, a decrease in body fat, more energy, stronger libido, and better overall wellness. Consequently, with RAD-140 athletes can get stronger, faster, and bigger safely. Additionally, it will not bring about the androgenic problems of testosterone in those seeking testosterone replacement therapy or those wanting a testosterone base in their cycles.

In addition to that, those who already suffer from low testosterone levels due to medical issues, or simply because they abused anabolic steroids in their past, will be able to use testolone as their testosterone replacement.

Side effects
RAD-140 does not have many of the side effects of anabolic steroids. For instance, the following are some of the undesired effects that you will avoid by using Testolone instead of anabolic steroids:

  • Androgenic side effects: many athletes complain about such side effects as lipid strain, liver issues, kidney issues, heart strain, aggression, insomnia, and changes in mood. In this regard, the main culprits are compounds like anadrol, halotestin, testosterone, and trenbolone.
  • Estrogenic side effects: for someone who is trying to achieve wellness and endurance enhancement, nothing is worse than having to feel like garbage all day from water retention. Unfortunately, certain anabolic steroids like testosterone, dianabol, and deca durabolin are notorious for aromatizing into estrogen. This will cripple heart health, add water retention, cause gynecomastia, and create a domino effect of side effects like high blood pressure and even insomnia.
  • Progestin and dihydronandrolone (DHN) side effects: steroids in the class of 19-nortestosterones (deca durabolin and trenbolone) can cause libido issues and prolactin/progesterone problems. This is an important factor to keep in mind, since many of the prolactin related side effects are very similar to the estrogenic ones, including gynecomastia (bitch tits).
  • Dihydrotestosterone effects: DHT derivatives like winstrol, masteron, and others can do a number on head hair follicles, which will result in head hair loss.
Apart from the above mentioned side effects, such problems as acne, mood swings, attitude changes, and prostate enlargement can take place with anabolic steroid use. However, testolone will come with none of those problems.
 
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Suppression
Anabolic steroids will suppress the HPTA to levels where the pituitary glands are barely functioning or do not work at all. On the other hand, RAD-140 has been shown in studies to be minimally suppressive, and it does not interact with the prostate in the same way as testosterone does.

Stacking and how to use
Testolone can be used as your 'testosterone base' in a steroid cycle, but this is not the only way of using it. The beauty part is that it will give you additional benefits without increasing side effects, so it is definitely a good addition to any steroid cycle. Furthermore, it can also be used as part of a SARMS stack, and if you want additional endurance and fat loss benefits, stack in Cardarine (GW) or Stenabolic (SR9009) with it.

Since it is minimally suppressive, RAD-140 can also be used solo or included in a bridge.

Half life
The half life of RAD-140 is estimated to be of 12-18 hours. Thus, once a day dosage would work just fine, but many choose to split dose twice a day.

Dosage
The proper starting dosage for testolone in men is 10 milligrams (mg) per day, and 5mg per day for females.
 
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Anyone tried running Rad-140 / Testolone at the same time as test?
On paper it sounds like it would allow for more ‘free’ test, or bioavilable, or potentially even less aromatization???
I’ve got a couple bags from SYN and as a TRT guy I’m afraid it’ll never get used unless I try the above theory….

Thoughts???
 
Anyone tried running Rad-140 / Testolone at the same time as test?
On paper it sounds like it would allow for more ‘free’ test, or bioavilable, or potentially even less aromatization???
I’ve got a couple bags from SYN and as a TRT guy I’m afraid it’ll never get used unless I try the above theory….

Thoughts???
I havent but I am about too.
I have been seeing that it is head to head effective for shrinking prostate. Also back in 2018 I used it OFF test and did notice an increase in my urine flow. I did stack it with another sarm and did take a relatively unneeded high dose. My Rad140 should be here in a few days. Ill keep you posted.
 
I havent but I am about too.
I have been seeing that it is head to head effective for shrinking prostate. Also back in 2018 I used it OFF test and did notice an increase in my urine flow. I did stack it with another sarm and did take a relatively unneeded high dose. My Rad140 should be here in a few days. I’ll keep you posted.
@CosmicJuiceBoxx I may have to run it alongside of you so we can compare notes. Lol damn I love this forum
 
So how does RAD-140 affect your liver values?
MINE specifically? Or in general?
Bull has a great write up on it….

 
MINE specifically? Or in general?
Bull has a great write up on it….


I did read the article and found nothing about how it affects the liver, just a brief line regarding steroids affecting liver among other things, and that is the only time the word liver shows up when you search it.

As an oral I would assume it's not easy on the liver but it's not discussed, unless I missed it...
 
I did read the article and found nothing about how it affects the liver, just a brief line regarding steroids affecting liver among other things, and that is the only time the word liver shows up when you search it.

As an oral I would assume it's not easy on the liver but it's not discussed, unless I missed it...
I will check my liver after I run it. Though results could be skewed as I will run TUDCA with it, just because why not. I did like 10 weeks of 20 & 30mg a day in winter 2018 into early 2019. Stacked with LGD3303. Ngl, one of the best my shoulders traps and back ever looked, unreal strength but again 30mg rad a day looking back, I wouldn't do that again, maybe for a week tops but again, Im going into it to relieve BPH symptoms of poor urination.
 
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