Arimidex, takes a bit of time to reach stable levels in the blood, but that doesn't mean it doesn't work on the first 0.25mg , because it does, consistently taking it on a schedule is where it works best to maintain a proper estrogen levels.
You can most definitely spot take it, meaning take anytime and it will do its job, although its a bit slower then aromasin. Ill explain.
X amount of testosterone to estrogen conversion vs the strength of the ai. If your conversion is more then the strength of the ai then you wont block all of the estrogen being converted. To know this you need to play around a bit.
Theres alot of factors that play in this like your calcium levels your thyroid condition your cortisol levels, liver condition, these all have an effect on how much you aromatize, and clear estrogen, Theres no one dosage for all
On 500mg test, depending on how you inject it, can also play a different role, everyday injections vs once a week vs 3 x a week will change the conversion, plus change the time it takes for estrogen to clear.
Everyday injections you may not even aromatize, by keepimg stable teat levels you will also keep estrogen in ratio to your testosterone.
A good start would be 0.25mg arimidex 3 times a week so 0.75 total. If you feel thats a bit to much drop to twice a week. Stay on a steady course and let the arimidex do its job. Then you can help keep your self in that target range that feels best.
Ok i could talk for hrs on this ill try to tie it up .
Aromasin, will kill x amount of estrogen vs the strength you take so 6mg 12.5mg 25mg will eliminate x amount of estrogen and from what iv found does this in a 9 to 12 hr window, for the remaining 20 hrs you get a bit of a estrogen blocking defense.
Arimidex, especially ugl labs i find when you take say 0.25mg it lowers the estrogen enzymes but does not eliminate any estrogen, but your own body has a chance to lower estrogen at this time because your blocking the conversion, but the strength of arimidex you take , does lower your circulation of estrogen will say, but from what iv found is roughly 2 days, they say 3 but ugl i find 2 days it holds it for , after those 2 days are up , your estrogen comes back to the level it was MINUS what cleared during the time it was blocking it. This is how it differs from Aromasin.
So if it were a race to see who had the lowest true estrogen by the end of the week, Aromasin wins everytime.
Close comparison for me in my opinion is.
25mg Aromasin = 1mg arimidex
12.5mg Aromasin = 0.5mg arimidex
6mg aromasin = 0.25mg arimidex.
Although they have different actions this is as close as bro science can get.