Histamine
Associated with arousal. It is often released in response to an allergic reaction. It can certainly "sedate" the patient when it is released, this is some of the thought process why tren and other compounds cause lethargy, it is 'believed' that the body is constantly releasing histamines into the bloodstream to fight off the allergens..aka "tren". Also this is medically theorized and makes sense as to explain "Tren COUGH". When the user injects tren, the body instantly releases several chemicals, including Histamine. It is such a sudden and large amount of release that the body interpets it as an "allergic reaction". It responds with symptoms such as coughing, itchy eyes, runny nose, swollen eyes, respiratory issues and shortness of breathe.
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- found that on another forum, he doesn’t cite any sources but it seems logical
that is people trying to connect the dots mostly and I believe misses on a few levels. Maybe more than a few. To be completely honest..... it’s all speculation as far as I can see. And this theory is just another that can be added to the list via the connect the dots application.
histamine response oversimplifies this event. And probably is mostly incorrect.
prostaglandins, bradykinin, histamines. All may play an interconnected complicated role here..... or not.
however to simply try to connect the dots to histamine is, I believe, short sighted and again incorrect. I have yet to see any credible source stating otherwise.
anecdotally speaking and in personal experience the symptoms experienced during both occurrences are significantly different. Anyone who has experienced both will know exactly what I mean. That coupled with the very short duration of symptoms experienced via a “tren cough” event lead me to believe again not histamine. Symptoms would be more diverse and longer lasting. Possibly worsening without administration of an anti-histamine. Possibly. Especially with repeated and frequent exposure. I have never heard even rumour of a steroid user suffering from anaphylaxis from steroids exclusively. Perhaps oil? Say if peanut or something known to cause such was administered. This would be extremely violent considering the administration path. But that’s a whole other topic of discussion really.
Another factor to consider here is if we are anticipating a histamine response exclusively, why would the “tren cough” symptoms only occur intermittently.... sometimes significantly so. This tends not to be the case in such matters and quite often worsen over repeated exposure to something that causes histamine to be released in the body.
Additionally one would certainly expect localized reaction at injection sites if there was something present in the administration that triggered a histamine response. Think wasp sting. This venom contains a fairly significant concentration of peptides that cause granules to release histamines. That is the redness and swelling. Coupled with further symptoms should the release be more significant right up to anaphylaxis.
There is much more that can be discussed here and obviously this is extremely elementary. Partly due to trying to keep this at a level where it can be consumed for thought..... mostly because of my limitations on the subject. And also because of lack of study in the area for obvious reasons.
In the end. Again. People trying to connect dots while not completely understanding the situation. Can I discount it wholly? No. But there is more than enough information out there that supports this is not true, or at the very least not completely understood and therefore does not hold water.
I compare this to the trenbolone oxidizes theory widely parroted on the forums. And oh boy did I ever learn a valuable lesson there. I had made that comment once and got called out and will never forget it. I did so without thinking and it was so bloody obvious.... well embarrassing. Lol.